This laboratory process identifies antibodies that assault pink blood cells. It exists in two main types: direct and oblique. The direct model detects antibodies already certain to the floor of pink blood cells, indicating an autoimmune hemolytic anemia, drug-induced hemolysis, or hemolytic illness of the new child. Conversely, the oblique model identifies free-floating antibodies within the serum able to binding to pink blood cells, usually employed in prenatal testing to detect antibodies that might trigger hemolytic illness in a fetus.
This assay is essential for diagnosing and managing circumstances the place the immune system targets pink blood cells, resulting in their untimely destruction. Precisely figuring out these antibodies helps clinicians tailor remedy methods, corresponding to immunosuppression or blood transfusions. Its growth revolutionized the understanding of hemolytic anemias and performed a significant function in stopping extreme issues, notably in newborns vulnerable to erythroblastosis fetalis. The check’s accessibility and reliability have made it an indispensable software in trendy hematology and transfusion drugs.
